Från New York Times :
In an interview that was included as a DVD extra, Mr. Wiseau said the title had “a special meaning” to him.
At the time, I thought about a special place, a private place, a place where you can be safe. And it’s not a room, but it’s the room. I thought and I think that a lot of people would relate to it. So the room is a place where you can go, you can have a good time, you have a bad time, and a safe place.
Här är extra DVD: