Det kanske inte har varit en avsiktlig referens till den komik som du nämnde, men Galactus hjälpte att besegra universums fara som kallas Abraxas .
Abraxas... spontaneously assumed the embodiment of destruction that was the counterpart to the very act of creation embodied by the being known as Eternity.... He soon began to cut a swath of terror through various alternate realities... Abraxas taunted the Fantastic Four with the inevitability of his coming.
Galactus took the Nullifer from Abraxas, giving it to Mister Fantastic who used the weapon, destroying himself and Abraxas.