Ja, Stan Lee sa att han var inspirerad av Jekyll / Hyde och Frankensteins monster
Lee förklarade detta i en intervju med Rolling Stone
When you read the first issue of the Incredible Hulk, it doesn’t seem like a superhero title at all – it feels more in the vein of the monster comics you had been writing beforehand. How conscious was that direction?
I was getting tired of the normal superheroes and I was talking to my publisher. He said, "What kind of new hero can we come up with?" I said, "How about a good monster?" He just walked out of the room. I remembered Jekyll and Hyde, and the Frankenstein movie with Boris Karloff and it always seemed to me that the monster was really the good guy; he didn't want to hurt anybody, but those idiots kept chasing him up the hill until he had to strike back. So why not get a guy who looks like a monster and really doesn't want to cause any harm. But he has to in self-defense, because people are always attacking him.